Hyperemesis Gravidarum: A Benign Condition of Pregnancy or a Challenging Metabolic Disorder?

Florentin, Matilda and Parthymos, Ioannis and Agouridis, Aris P and Liamis, George (2020) Hyperemesis Gravidarum: A Benign Condition of Pregnancy or a Challenging Metabolic Disorder? European Journal of Case Reports in Internal Medicine, 7 (12). pp. 1-4. ISSN ISSN: 2284-2594

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Abstract

Hyperemesis gravidarum (HG) is a complication mainly of the first trimester of pregnancy, which sometimes leads to metabolic disorders such as hypovolemia and acute kidney injury (AKI). Herein, we present the case of a 25-year-old woman at week 10 of gestation who exhibited a constellation ofsevere abnormalities, namely AKI (serum creatinine 6.15 mg/dl), transaminasemia (serum aminotransferases >1,000 IU/l), alkalemia (arterial pH7.667), hyponatremia (serum sodium 117 mEq/l), hypochloremia (serum chloride 54 mEq/l),hypokalemia (serum potassium 2.2 mEq/l) and hyperuricemia (serum uric acid 20 mg/dl). Despite a thorough work-up, no other disorder was found apart from HG. All symptoms and metabolic abnormalities resolved with targeted administration of intravenous fluids. The differential diagnosis of these disorders and therapeutic challenges are discussed.

Item Type: Article
Uncontrolled Keywords: Acute kidney injury, alkalemia, hepatitis, hyperemesis gravidarum, hypokalemia, hyponatremia, hypovolemia
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 20 Dec 2021 14:27
Last Modified: 20 Dec 2021 14:27
URI: http://eprints.bice.rm.cnr.it/id/eprint/21091

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