Rêgo Salgueiro, Fábio and Cunha, Paulo and Miranda, Diana and Pereira, Tatiana and Pontes, Filipa and Monteiro, Joana and Caetano, Ana (2021) Clear Cell Carcinoma of the Thymus: An Improbable Enemy. European Journal of Case Reports in Internal Medicine, 8 (2). pp. 1-3. ISSN ISSN: 2284-2594
|
Text
2224-Article Text-20865-1-10-20210224.pdf - Published Version Download (360kB) | Preview |
Abstract
Introduction: Thymic clear cell carcinoma is the most uncommon subtype of thymic carcinoma, with 20 cases reported worldwide.Case description: We present the case of a 61-year-old female with dyspnoea and chest pain for 2 days. Computed tomography (CT) angiography showed pulmonary thromboembolism and the existence of mediastinal and bilateral hilar lymphadenopathy, the largest infracarinal with an inferior axis of 25 mm, and also, micronodules on the left pulmonary parenchyma. The patient was admitted for aetiological assessment and underwent anticoagulant therapy. After a month, she had an ischaemic stroke, the sequelae of which proved to be fatal. The autopsy showed a mass in the superior-anterior mediastinum, with dimensions of 11×8×6 cm, corresponding to a thymus signet ring cell primary carcinoma. The immunohistochemistry study revealed that this mass was positive for AE1/AE3, CK5/6 and CK7.Conclusion: The clinical, morphological and immunophenotypic diversity of this tumour makes its diagnosis a difficult multidisciplinary challenge, which requires a high level of clinical knowledge and accurate imaging and histological investigation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Thymic carcinoma, mediastinal tumour |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 20 Dec 2021 15:10 |
| Last Modified: | 20 Dec 2021 15:10 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21172 |
Actions (login required)
 |
View Item |
