Abu Shtaya, Aasem and Cohen, Shai and Kogan, Yana and Shteinberg, Michal and Sagool, Ori (2021) Crohn’s Disease with Atypical Extra-Intestinal Manifestations Developing Under Treatment with Vedolizumab. European Journal of Case Reports in Internal Medicine, 8 (2). pp. 1-4. ISSN ISSN: 2284-2594
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Abstract
Crohn’s disease is a chronic inflammatory bowel disease that can affect any part of the GI tract, which is frequently associated with extra-intestinal manifestations. Pulmonary parenchymal disease is very uncommon and usually considered to be debilitating and harder to diagnose. Pulmonary granulomas are rarely described in the literature as a complication of Crohn’s disease. Here, we present a patient with Crohn’s disease exacerbation who developed granulomatous lung disease under treatment with vedolizumab. Our case may add evidence to the emerging theory that gut-selective biologic agents could lead to upregulation of some pro-inflammatory factors leading to the evolution of pulmonary disease.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Crohn’s disease, granuloma, vedolizumab, infliximab |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 20 Dec 2021 15:13 |
| Last Modified: | 20 Dec 2021 15:13 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21177 |
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