Successful Use of a GLP-1 Receptor Agonist as Add-on Therapy to Sulfonylurea in the Treatment of KCNJ11 Neonatal Diabetes

Hindsø, Morten and Martinussen, Christoffer and Saur Svane, Maria and Veedfald, Simon and Gade-Rasmussen, Birthe and Hansen, Torben and Madsbad, Sten (2021) Successful Use of a GLP-1 Receptor Agonist as Add-on Therapy to Sulfonylurea in the Treatment of KCNJ11 Neonatal Diabetes. European Journal of Case Reports in Internal Medicine, 8 (3). pp. 1-4. ISSN ISSN: 2284-2594

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Abstract

Sulfonylurea monotherapy is the standard treatment for patients with the most common form of permanent neonatal diabetes, KCNJ11neonatal diabetes, but it is not always sufficient. For the first time, we present a case of successful use of a GLP-1 receptor agonist as add-on therapy in the treatment of a patient with KCNJ11 neonatal diabetes and insufficient effect of sulfonylurea monotherapy. Good glycaemic control was maintained with a HbA1c level of 48 mmol/mol (6.5%) at the end of 26 months’ follow-up.

Item Type: Article
Uncontrolled Keywords: Neonatal diabetes, KCNJ11, sulfonylurea, GLP-1
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 20 Dec 2021 15:30
Last Modified: 20 Dec 2021 15:30
URI: http://eprints.bice.rm.cnr.it/id/eprint/21193

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