Ozer, Muhammet and Juneja, Kirti and Mahdi, Mohammed and Jannareddy, Namrata and Gandhi, Neel (2021) Unilateral Proptosis due to Orbital Metastasis of Paratesticular Leiomyosarcoma. European Journal of Case Reports in Internal Medicine, 8 (3). pp. 1-3. ISSN ISSN: 2284-2594
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Abstract
Paratesticular leiomyosarcomas are uncommon malignant tumours that originate from smooth muscle and show aggressive tumour behaviour due to a high incidence of local recurrence and distant metastasis. Orbital metastasis is also rare and associated with a poor prognosis. Clinical suspicion plays an essential role in the diagnosis of orbital leiomyosarcoma because of its uncommon presentation. Comprehensive neuroimaging and histopathological work-up are warranted for definitive diagnosis and management. To date, surgical resection remains the best curative treatment. However, leiomyosarcomas are usually friable and unencapsulated, which makes surgery challenging. Also, whether adjunctive chemotherapy will alter the long-term prognosis remains to be determined. Herein, we report the case of a middle-aged man who presented with proptosis and decreased vision, who was subsequently diagnosed with metastatic orbital leiomyosarcoma from a primary paratesticular tumour. We performed orbital enucleation with negative margins. The patient is currently under systemic pazopanib chemotherapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Unilateral proptosis, orbital metastasis, paratesticular leiomyosarcoma, ocular enucleation, neuroimaging |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 21 Dec 2021 14:56 |
| Last Modified: | 21 Dec 2021 14:56 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21214 |
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