Disseminated Blastomycosis Presenting with Spontaneous Coronary Artery Dissection

Sehgal, Rahul and O'Cochlain, D Fearghas and Virata, Andrew R and Singh, Gurpreet (2021) Disseminated Blastomycosis Presenting with Spontaneous Coronary Artery Dissection. European Journal of Case Reports in Internal Medicine, 8 (4). pp. 1-4. ISSN ISSN: 2284-2594

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Abstract

Spontaneous coronary artery dissection (SCAD) is increasingly recognized as an important cause of acute coronary syndrome (ACS) and myocardial infarction (MI) in individuals with few or no known atherosclerotic risk factors. While systemic autoimmune inflammatory disorders are associated with precipitating SCAD, the role of infection-induced systemic inflammation in SCAD is not well defined. We present the case of a 49-year-old Caucasian woman with ST-elevation myocardial infarction (STEMI) diagnosed as SCAD from a severe systemic inflammatory response related to disseminated blastomycosis. Punch biopsy of a skin lesion and synovial fluid culture confirmed Blastomyces dermatitidis. This case suggests the possibility of systemic infection-induced inflammation as a precipitating factor in SCAD pathogenesis similar to autoimmune inflammatory disorders.

Item Type: Article
Uncontrolled Keywords: Spontaneous coronary artery dissection, ST-elevation myocardial infarction, blastomycosis
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 21 Dec 2021 15:00
Last Modified: 21 Dec 2021 15:00
URI: http://eprints.bice.rm.cnr.it/id/eprint/21220

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