Chouk, Mickaël and Halb, Alexandre and Mekhail, Christine and Godot, Amélie and Verhoeven, Frank and Prati, Clément and Wendling, Daniel (2021) Efficacy of Rituximab on Rheumatoid Leptomeningitis as the First Symptom of Rheumatoid Arthritis. European Journal of Case Reports in Internal Medicine, 8 (4). pp. 1-4. ISSN ISSN: 2284-2594
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Abstract
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized mainly by arthritis, with the possible occurrence of extra-articular manifestations. We report the case of a patient who developed leptomeningitis as the first sign of RA, one year before the diagnosis of RA. Methylprednisolone 1000 mg was given intravenously. Because of the onset of seizures and cognitive impairment, rituximab was started. After three cycles of rituximab (1000 mg on day 0 and 1000 mg on day 15, every 6 months), neurological clinical examination, MRI and electroencephalogram findings were significantly improved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Rheumatoid arthritis, rheumatoid meningitis, rituximab, leptomeningitis, seizure |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 21 Dec 2021 15:01 |
| Last Modified: | 21 Dec 2021 15:01 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21221 |
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