Granulomatosis with Polyangiitis: Recurrence or Treatment Consequences?

Diegues, Andreia and Tavares, Joana and Sá, Diogo and Oliveira, João and Fernandes, Diana and Santos, Josefina and Rocha, Guilherme (2021) Granulomatosis with Polyangiitis: Recurrence or Treatment Consequences? European Journal of Case Reports in Internal Medicine, 8 (4). pp. 1-5. ISSN ISSN: 2284-2594

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Abstract

Granulomatosis with polyangiitis (GPA) is the most common antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We describe the case of a 38-year-old woman with relapsing GPA who presented with intracranial hypertension, followed by the appearance of cavitated lung nodules despite treatment with azathioprine. Clinical improvement and ANCA titre reduction were observed after rituximab treatment. We report a rare form of GPA relapse and highlight the challenge of following-up patients with GPA, in whom can be hard to distinguish relapse from the consequences of long-term immunosuppression.

Item Type: Article
Uncontrolled Keywords: ANCA-PR3-associated vasculitis, granulomatosis with polyangiitis, intracranial hypertension, lung nodules
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 21 Dec 2021 15:02
Last Modified: 21 Dec 2021 15:02
URI: http://eprints.bice.rm.cnr.it/id/eprint/21223

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