Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy

Lorenzo-Villalba, Noel and Andrès, Emmanuel and Meyer, Alain (2021) Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy. European Journal of Case Reports in Internal Medicine, 8 (6). pp. 1-3. ISSN ISSN: 2284-2594

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Abstract

We report a case of anti-HMGCR myopathy mimicking limb-girdle muscular dystrophy in a 27-year-old male patient with no history of statin intake and presenting with a chronic onset form over 3 years. Treatment with prednisone and methotrexate was initiated with an insufficient response, so intravenous immunoglobulin was added. One year after initial treatment was started, as levels of creatine kinase (CK) were >1000 U/l, treatment with rituximab was added. Despite a 3-year delay before treatment, muscle strength improved even though CK levels remain elevated.

Item Type: Article
Uncontrolled Keywords: Anti-HMG-CoA reductase, myopathy
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 25 Jan 2022 15:38
Last Modified: 25 Jan 2022 15:38
URI: http://eprints.bice.rm.cnr.it/id/eprint/21268

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