Optimization of the theoretical dose distribution in the “Spread Out Bragg Peak” (SOBP) region in proton therapy by means of semi-analytical techniques

Nichelatti, E. and Ronsivalle, C. and Picardi, L. and Montereali, R. M. (2021) Optimization of the theoretical dose distribution in the “Spread Out Bragg Peak” (SOBP) region in proton therapy by means of semi-analytical techniques. Il nuovo cimento C, 44 (4-5). pp. 1-4. ISSN 1826-9885

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Abstract

Proton therapy uses proton beams to destroy cancer cells. Since the energy deposition of protons peaks at the end of the trajectory (Bragg peak), healthy tissues close to the target are partially spared. In clinical practice, beams of different energies are composed to obtain a broadened peak (SOBP, Spread Out Bragg Peak) to treat the entire lesion region in a uniform manner. In the framework of the TOP-IMPLART project (linear accelerator for proton therapy under construction at ENEA-Frascati), we present a semi-analytical method that allows to optimize SOBP uniformity for two different energy-modulation techniques, passive and active.

Item Type:	Article
Subjects:	500 Scienze naturali e Matematica > 530 Fisica
Depositing User:	Marina Spanti
Date Deposited:	20 Sep 2021 09:54
Last Modified:	20 Sep 2021 09:54
URI:	http://eprints.bice.rm.cnr.it/id/eprint/21362

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