Management and Treatment of Late-Onset Multiple Sclerosis

Realmuto, Sabrina and Accurso, Giuseppe and Cammarata, Enrico and Romano, Marcello Calogero (2021) Management and Treatment of Late-Onset Multiple Sclerosis. European Journal of Case Reports in Internal Medicine, 8 (Sup 2). pp. 37-39. ISSN 2284-2594

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Abstract

Multiple sclerosis (MS) with clinical onset after the age of 50 years is unusual and frequently misdiagnosed. Ageing is associated with diverse immune changes also known as immunosenescence, and a higher risk of comorbidities and infections, which need to be considered when planning medical treatments. We describe the case of a 69-year-old woman with late-onset relapsing-remitting MS. Beyond the diagnostic difficulty and specific therapy for MS, we also addressed the management of symptoms, such as spasticity. Our case report confirmed the good safety profile of nabiximols in older age also. Progress in imaging and biomarker assessment has helped to distinguish MS from mimicry disease, which is important for improving disease management in the longer term.

Item Type: Article
Uncontrolled Keywords: Multiple sclerosis, late onset, disease-modifying therapy
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 19 Jan 2022 17:07
Last Modified: 19 Jan 2022 17:07
URI: http://eprints.bice.rm.cnr.it/id/eprint/21483

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