Primary Central Nervous System Lymphoma with Exclusive Leptomeningeal Involvement: The Diagnostic Challenge of a Rare Presentation of an Uncommon Disease

Santos, Miguel and Pires, Tatiana and Rodrigues, Ana and Bandeira, Adriana and Albuquerque, Ana and Santos, Flávia and Magalhães, Miriam and Jesus Banza, Maria (2022) Primary Central Nervous System Lymphoma with Exclusive Leptomeningeal Involvement: The Diagnostic Challenge of a Rare Presentation of an Uncommon Disease. European Journal of Case Reports in Internal Medicine, 9 (1). pp. 1-3. ISSN 2284-2594

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Abstract

Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extra-nodal non-Hodgkin lymphoma (NHL). It must be confined to the brain, eyes, spinal cord or leptomeninges without systemic involvement at the time of diagnosis. Disease confined to the cerebrospinal fluid (CSF) is a rare form of presentation and poses a particular diagnostic challenge. We present the case of an 82-year-old man admitted to hospital because of an acute confusional state, later revealed to be due to PCNSL with exclusive leptomeningeal involvement. The diagnostic process was further impaired (or, perhaps, aided?) by the onset of a COVID-19 outbreak on the ward.

Item Type: Article
Uncontrolled Keywords: Primary central nervous system lymphoma, leptomeningeal lymphoma
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 15 Mar 2022 17:02
Last Modified: 15 Mar 2022 17:02
URI: http://eprints.bice.rm.cnr.it/id/eprint/21679

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