Primary Adrenal Lymphoma: When B Symptoms Appear Hand in Hand with Adrenal Masses

Lopes Sousa, David and Santos, Sandra D and Pina Cabral, João and Velho, Ricardo and Teixeira, Ana Sofia and Ribeiro, Pedro (2022) Primary Adrenal Lymphoma: When B Symptoms Appear Hand in Hand with Adrenal Masses. European Journal of Case Reports in Internal Medicine, 9 (1). pp. 1-3. ISSN 2284-2594

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Primary adrenal lymphoma (PAL) is a very rare type of non-Hodgkin’s lymphoma (NHL). Herein, we report a case of NHL of both adrenal glands in a 69-year-old man. The patient was admitted because of a 1-month history of B symptoms and symptomatic hypotension. Biochemical analysis showed normocytic normochromic anaemia, hyponatraemia, hyperkalaemia, and elevated lactate dehydrogenase, C-reactive protein and D-dimers. A computed tomography scan revealed bilateral enlargement of the adrenal glands. There was no evidence of endocrine adrenal dysfunction. The mass in the right adrenal gland was biopsied and histopathology identified a diffuse large B-cell lymphoma of the activated B-cell subtype. A positron emission tomography 18F-fluorodeoxyglucose scan showed intensive hypermetabolic lesions involving both adrenal glands, as well as other locations, with higher uptake in the adrenal glands. Taken together, these findings suggested the diagnosis of PAL. The patient responded favourably to debulking therapy and is currently undergoing chemotherapy.

Item Type: Article
Uncontrolled Keywords: Primary adrenal lymphoma, adrenal mass, positron emission tomography
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 15 Mar 2022 16:55
Last Modified: 15 Mar 2022 16:55

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