A Case of Severe COVID-19 in a Patient with Good's Syndrome

Duarte, Maria and Faria, Luciana and Patronillo, Catarina and da Costa Fernandes, Sónia and Seara, Vera (2021) A Case of Severe COVID-19 in a Patient with Good's Syndrome. European Journal of Case Reports in Internal Medicine, 8 (10). pp. 1-3. ISSN 2284-2594

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Good’s syndrome is a rare adult-onset combined immunodeficiency. The association of hypogammaglobulinaemia with a history of recurrent infectious or autoimmune manifestations in a middle-aged patient with evidence of a mediastinal mass should lead to the clinical suspicion of Good’s syndrome. The mortality rate associated with infectious complications is high. Thus, although it is rare, the disease should be diagnosed early so that proper treatment can be started. Thymectomy and immunoglobulin replacement are the main therapeutic strategies. We describe the case of a patient with a history of thymoma and recurrent respiratory infections, with a late diagnosis of Good’s syndrome in the context of severe organizing pneumonia secondary to COVID-19

Item Type: Article
Uncontrolled Keywords: COVID-19, Good’s syndrome, immunoglobulin
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Feb 2022 09:54
Last Modified: 17 Feb 2022 09:54
URI: http://eprints.bice.rm.cnr.it/id/eprint/21718

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