Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination

Maadarani, Ossama and Bitar, Zouheir and Ashkanani, Abdelaziz and Elzoueiry, Mahmoud and Elhabibi, Mohamad and Gohar, Mohamad and Almuwaizri, Mohamad and Shoeb, Sania and Alsaddah, Jadan (2021) Cardiac Sodium Channel Blockade Due to Antiepileptic Drug Combination. European Journal of Case Reports in Internal Medicine, 8 (10). pp. 1-4. ISSN 2284-2594

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Drugs that inhibit voltage-dependent sodium channels are commonly used to treat epilepsy. Old and novel antiepileptic drugs are used either as monotherapy or in combination to control epilepsy. For a long time, carbamazepine has been used as the first choice for the treatment of simple and complex partial seizures. In the USA, lacosamide was approved in October 2008 as an adjunctive treatment for partial-onset seizures. We describe the effect of two sodium channel blockers on the heart of a patient with epilepsy.

Item Type: Article
Uncontrolled Keywords: Sodium channel blockers, lacosamide, electrocardiogram
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 17 Feb 2022 12:12
Last Modified: 17 Feb 2022 12:12

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