Gaudêncio, Margarida and Parente, Catarina and Lameiras, Ana Catarina and Marinho, António (2021) Mixed Cryoglobulinaemia Vasculitis Treated with Obinutuzumab in a Patient Allergic to Rituximab. European Journal of Case Reports in Internal Medicine, 8 (11). pp. 1-3. ISSN 2284-2594
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Abstract
Cryoglobulinaemia is defined as the presence of cryoglobulins in the serum, which are immunoglobulins that reversibly precipitate and form a gel when the temperature is <37ºC. Autoimmune diseases such as Sjogren’s syndrome, systemic lupus erythematosus and rheumatoid arthritis could be associated with mixed cryoglobulinaemia vasculitis (MCV). The treatment of MCV generally consists of glucocorticoids, cytotoxic agents such as cyclophosphamide, plasmapheresis or anti-CD20 monoclonal antibodies including rituximab. Here, we present a case of a 60-year-old woman who developed type II MCV in the context of overlap autoimmune disease and who has been treated with a new anti-CD20 agent, obinutuzumab.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Mixed cryoglobulinaemia, overlap syndrome, autoimmune diseases, remission, vasculitis, obinutuzumab |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 21 Feb 2022 12:53 |
| Last Modified: | 21 Feb 2022 12:53 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21740 |
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