Chronic Lymphocytic Leukaemia: Rare Involvement of the Central Nervous System

Amado, Carolina and Duarte, Valter and Silva Leal, Mariana and Cruz, Margarida and Ferreira, Gisela (2021) Chronic Lymphocytic Leukaemia: Rare Involvement of the Central Nervous System. European Journal of Case Reports in Internal Medicine, 8 (11). pp. 1-3. ISSN 2284-2594

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Involvement of the central nervous system, although uncommon, is one of the most frequent extramedullary manifestations of chronic lymphocytic leukaemia (CLL). Various conditions can lead to neurological symptoms in CLL patients and distinguishing between clinically significant CLL involvement of the CNS and other aetiologies can be challenging.The authors report the case of a 90-year-old woman with a previous diagnosis of low-risk CLL who presented to the emergency room with altered mental status. After the most frequent causes were ruled out and considering the underlying disease, CNS infiltration by clonal B-cells was hypothesised and later confirmed. Treatment was initiated, but the patient died soon afterwards.

Item Type: Article
Uncontrolled Keywords: Chronic lymphocytic leukaemia, central nervous system
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 21 Feb 2022 12:59
Last Modified: 21 Feb 2022 12:59

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