Severe Hypertriglyceridaemia Leading to Factitious Hypobicarbonataemia

Roy, Sasmit and Ashraf, Mohammed and Kang, Satbyul Sophia and Ayala, Raul and Adapa, Sreedhar (2021) Severe Hypertriglyceridaemia Leading to Factitious Hypobicarbonataemia. European Journal of Case Reports in Internal Medicine, 8 (12). pp. 1-3. ISSN 2284-2594

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Anion gap metabolic acidosis is a laboratory finding commonly encountered in patients with sepsis, diabetic ketoacidosis, acute kidney injury and toxic alcohol ingestion. Serum blood chemistry assessment detects this abnormality. However, this can be falsely low in situations of high triglyceride levels due to lipid interference with measurement of the bicarbonate levels and through volume displacement by these large molecules. Arterial blood gas analysis and a lipid panel are required to confirm accurate bicarbonate levels. Clinicians handling acid-base disorders in hospitalized patients need to be aware of this spurious laboratory value to avoid unnecessary tests and to determine accurate total bicarbonate levels.

Item Type: Article
Uncontrolled Keywords: Factitious hypobicarbonataemia, metabolic acidosis
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 15 Mar 2022 16:49
Last Modified: 15 Mar 2022 16:49

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