Leukaemic Ascites and Peritoneal Myeloid Sarcoma: Rare but Not Impossible

Landeiro, Luís and Gonçalves, Tiago Neto and Proença, Margarida and Nunes, Albertina and Bayão Horta, Alexandra (2022) Leukaemic Ascites and Peritoneal Myeloid Sarcoma: Rare but Not Impossible. European Journal of Case Reports in Internal Medicine, 9 (2). pp. 1-4. ISSN 2284-2594

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A myeloid sarcoma is an extramedullary tumour arising from infiltration by leukemic cells at an anatomic site other than the bone marrow. Most commonly it precedes acute myeloid leukaemia but occasionally occurs simultaneously. It may also be associated with myeloproliferative neoplasms, myelodysplastic syndrome and the blast phase of chronic myeloid leukaemia.The most common sites for extramedullary tumours are bone, periosteum, soft tissue, lymph node and skin. Although this disease can affect a wide range of body sites, there are very few reports of peritoneal myeloid sarcoma or cavity effusion.The authors present the case of a 68-year-old man with myelodysplasia-related acute myeloid leukaemia and peritoneal myeloid sarcoma with myeloid ascites. The definitive diagnosis is challenging, requires a high level of suspicion, and relies on the exclusion of all alternative diagnoses and especially on complementary tests such as flow cytometry and immunohistochemistry analysis of ascitic fluid in order to detect the immature myeloid cells.

Item Type: Article
Uncontrolled Keywords: Peritoneal myeloid sarcoma, leukemic ascites
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 14 Apr 2022 12:33
Last Modified: 14 Apr 2022 12:33
URI: http://eprints.bice.rm.cnr.it/id/eprint/21796

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