Di Natale, Marilena and Bennici, Carmelo and Biondo, Girolama and Masullo, Tiziana and Monastero, Calogera and Tagliavia, Marcello and Torri, Marco and Costa, Salvatore and Ragusa, Maria Antonietta and Cuttitta, Angela and Nicosia, Aldo (2019) Aberrant gene expression profiles in Mediterranean sea urchin reproductive tissues after metal exposures. Chemosphere, 216. pp. 48-58. ISSN 00456535
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Abstract
Marine organisms are exposed to numerous pollutants. To evaluate the effects of metal exposure at molecular level in reproductive tissues, we profiled the sea urchin transcriptional response after non-lethal exposures using pathway-focused mRNA expression analyses. We show that exposures to relatively high concentrations of both essential and toxic metals hugely affected the gonadic expression of several genes involved in stress-response, detoxification, transcriptional and post-transcriptional regulation, without significant changes in gonadosomatic indices. Even though treatments did not result in reproductive tissues visible alterations, metal exposures negatively affected the main mechanisms of stress-response, detoxification and survival of adult P. lividus. Additionally, transcriptional changes observed in P. lividus gonads may cause altered gametogenesis and maintenance of heritable aberrant epigenetic effects.
| Item Type: | Article |
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| Subjects: | 500 Scienze naturali e Matematica > 570 Scienze della vita; Biologia |
| Depositing User: | Dr Tiziana Masullo |
| Date Deposited: | 13 Jul 2023 08:40 |
| Last Modified: | 13 Jul 2023 08:40 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/22370 |
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