Non-invasive brain cortex hemodynamic monitoring: A step towards motor disorder assessment via TD fNIRS

Frabasile, L. and Lacerenza, M. and Buttafava, M. and Spinelli, L. (2023) Non-invasive brain cortex hemodynamic monitoring: A step towards motor disorder assessment via TD fNIRS. Il nuovo cimento C, 46 (4). pp. 1-4. ISSN 1826-9885

ncc12697.pdf - Published Version

Download (205kB) | Preview
Official URL:


The state of the art in diagnosing motor impairments involves looking for anomalies as the patient performs particular movements. However, subjectivity of perception, which is influenced by the operator’s experience, has an impact on this procedure. A more rigorous approach involves monitoring cerebral response to motor stimuli by functional Magnetic Resonance Imaging (fMRI). However, given the bulkiness of current fMRI devices, this solution forces the subject to maintain a static condition, limiting the range of response. Moreover, the temporal resolution of such acquisition is often sub-optimal in following fast hemodynamic variations in short motor tasks. In this framework, time-domain functional near-infrared spectroscopy (TD fNIRS) that exploits the diffusion of picosecond laser pulses in cerebral tissue allows for quantitative and non-invasive acquisition of brain functional activity. Given the latest hardware development, it is now possible to exploit compact and wearable TD-fNIRS devices allowing for real time brain monitoring of unconstrained moving subjects. To assess the potential of the TD fNIRS technique in the field of motor disorders, we studied motor cortex hemodynamic response functions on healthy subjects performing standard physiotherapy protocols and simple motor tasks including goal-oriented and non-goal-oriented activities.

Item Type: Article
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 08 Mar 2024 13:48
Last Modified: 08 Mar 2024 13:48

Actions (login required)

View Item View Item