The effects of smoking on the tear film and on soft contact lenses

Miglio, F. and Borghesi, A. and Zeri, F. and Ponzini, E. and Tavazzi, S. (2023) The effects of smoking on the tear film and on soft contact lenses. Il nuovo cimento C, 46 (5). pp. 1-4. ISSN 1826-9885

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Smoking is frequently associated with systemic and ocular diseases. Considering the fundamental role in eye health of the precorneal tear fluid, its analysis could offer unique contributions to gather information on ocular status. Smoking has a negative effect on tear film stability and quality by affecting different components, which can be assessed only by multiple tests. In addition, smoking is a risk factor for microbial keratitis and corneal infiltrates in contact lens (CL) wearers. In this work, the interaction between nicotine and CL materials is analysed. CLs belonging to the FDA groups I, II, IV, and V were incubated in a nicotine solution for 24 hours. The amount of absorbed nicotine per CL was monitored by ultraviolet spectrophotometry, normalizing it to the mass of the hydrated CL. Group IV and V CLs displayed the highest and lowest nicotine absorption, respectively. The results suggest that CL affinity for nicotine could be ascribed to the interaction between the positive charge of nicotine pyrrolidine nitrogen and the negative charges of the CLs.

Item Type: Article
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 15 Mar 2024 15:44
Last Modified: 15 Mar 2024 15:44

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