Oscillatory brain activity in vegetative and minimally conscious state during a sentence comprehension task

Schabus, Manuel and Pelikan, Christoph and Chwala-Schlegel, Nicole and Weilhart, Katharina and Roehm, Dietmar and Donis, Johann and Michitsch, Gabriele and Pichler, Gerald and Klimesch, Wolfgang (2011) Oscillatory brain activity in vegetative and minimally conscious state during a sentence comprehension task. Functional Neurology, 26 (1). pp. 31-36. ISSN 1971-3274

PDF portiere.pdf - Published Version Restricted to Repository staff only Download (723kB)

Abstract

Patients with altered states of consciousness continue to constitute a major challenge in terms of clinical assessment, treatment and daily management. Furthermore, the exploration of brain function in severely brain-damaged patients represents a unique lesional approach to the scientific study of consciousness. Electroencephalography is one means of identifying covert behaviour in the absence of motor activity in these critically ill patients. Here we focus on a language processing task which assesses whether vegetative (n=10) and minimally conscious state patients (n=4) (vs control subjects, n=14) understand semantic information on a sentence level (“The opposite of black is... white/yellow/nice”). Results indicate that only MCS but not VS patients show differential processing of unrelated (“nice”) and antonym (“white”) words in the form of parietal alpha (10-12Hz) event-related synchronization and desynchronization (ERS/ERD), respectively. Controls show a more typical pattern, characterized by alpha ERD in response to unrelated words and alpha ERS in response to antonyms

Item Type:	Article
Uncontrolled Keywords:	Disorders of consciousness, electroencephalography, event-related synchronization/desynchronization, minimally conscious state, sentence processing, vegetative state
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) > 616.8047548 Sistema Nervoso – Risonanza magnetica nucleare (Classificare qui: Neuroimaging, Neuroimaging funzionale, Cervello - Risonanza magnetica funzionale, Cervello - Risonanza magnetica per immagini)
Depositing User:	Danilo Dezzi
Date Deposited:	30 Sep 2011 15:20
Last Modified:	03 Feb 2016 09:50
URI:	http://eprints.bice.rm.cnr.it/id/eprint/3493

Actions (login required)

View Item