Psychosexual well-being in women using oral contraceptives containing drospirenone

Nappi, Rossella Elena and Albani, Francesca and Tonani, Silvia and Santamaria, Valentina and Pisani, Carla and Terreno, Erica and Martini, Ellis and Polatti, Franco (2009) Psychosexual well-being in women using oral contraceptives containing drospirenone. Functional Neurology; New Trends in Interventional Neurosciences, 24 (2). pp. 71-75. ISSN 1971-3274

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Abstract

Considerable advances have been made in hormonal contraception in recent years, geared at maximizing compliance and minimizing discontinuation. In oral contraceptive (OC) formulations, the estrogenic component, generally ethinyl estradiol (EE), has been reduced significantly and newer progestins like dienogest and drospirenone (DRSP), compounds with different molecular structures, have been introduced; in addition, new regimens (extended, flexible, 24/4 formats instead of the standard 21/7 format) and innovative delivery systems (vaginal rings, transdermal patches, subcutaneous implants and intrauterine devices) are available. The multitude of choices allows hormonal contraception to be tailored to the individual woman in order to obtain non-contraceptive benefits, without significant side effects, and also a favorable risk/benefit profile for her general and reproductive health. Over the past few years, new OC formulations combining DRSP (3 mg), a unique progestin with both antimineralocorticoid and antiandrogenic activities, with estrogen (30 mcg or 20 mcg EE), in two regimens (24/4 and 21/7) of active pills in a 28-day cycle, have shown positive effects on water retention-related weight gain and physical, emotional and psychosexual well-being. It seems likely that the use of a low-dose, well-balanced OC and the shorter 4-day hormone-free interval may minimize the side effects that can impair quality of life and thus increase women’s compliance with hormonal contraception therapy

Item Type:	Article
Uncontrolled Keywords:	Drospirenone, oral contraceptives, premenstrual disorders, sexual function, 21/7 regimen, 24/4 regimen
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia)
Depositing User:	Danilo Dezzi
Date Deposited:	09 Jul 2012 09:55
Last Modified:	09 Jul 2012 09:55
URI:	http://eprints.bice.rm.cnr.it/id/eprint/3609

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