Psychiatric symptoms related to the use of lamotrigine: a review of the literature

Villari, Vincenzo and Rocca, Paola and Frieri, Tiziana and Bogetto, Filippo (2008) Psychiatric symptoms related to the use of lamotrigine: a review of the literature. Functional Neurology; New Trends in Interventional Neurosciences, 23 (3). pp. 133-136. ISSN 1971-3274

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Abstract

Lamotrigine is an established anticonvulsant agent and also an effective maintenance therapy for bipolar disorder. In Italy it is approved for the treatment of epilepsy with partial seizures, partial seizures with secondary generalization and generalized seizures, both in monotherapy and as an add-on therapy in patients with refractory epilepsy; it is also approved for the prevention of depressive episodes in patients with bipolar disorder with a predominant depressive component. Lamotrigine is generally well tolerated; however, some psychiatric problems have been reported in patients using the drug to treat mental disorders (mainly bipolar) or epilepsy. The clinical features of these psychiatric side effects are: affective switches, full acute psychotic episodes, and hallucinations. In conclusion, lamotrigine is an effective drug, very useful in the therapy of epilepsy and mood disorders, but clinicians have to be aware of the risk that it can induce psychiatric symptoms or acute episodes

Item Type:	Article
Uncontrolled Keywords:	Acute psychosis, bipolar disorder, depression, epilepsy, lamotrigine
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia)
Depositing User:	Danilo Dezzi
Date Deposited:	08 May 2012 13:06
Last Modified:	08 May 2012 13:06
URI:	http://eprints.bice.rm.cnr.it/id/eprint/3690

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