The importance of neuronal stimulation in central nervous system plasticity and neurorehabilitation strategies

Boltes Cecatto, Rebeca and Chadi, Gerson (2007) The importance of neuronal stimulation in central nervous system plasticity and neurorehabilitation strategies. Functional Neurology; New Trends in Interventional Neurosciences, 22 (3). pp. 137-143. ISSN 1971-3274

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Abstract

Basic neuroscience has demonstrated new mechanisms of neuroplasticity in the healthy and the lesioned brain. Post injury, behavioral experience and neuronal stimulation-based therapy seem to play an adaptive role in the injured brain, modifying the functional organization of remaining cortical tissue and leading to clinical improvements. A better understanding of the cellular and molecular mechanisms underlying human neuroplasticity might benefit neurorehabilitation strategies designed to promote recovery of function. We review some of the main results from animal experimental and human clinical studies focusing on mechanisms of reorganization of the motor cortex in response to injury and highlight different available approaches used to modulate and to evaluate motor cortical plasticity. Finally, we discuss how knowledge on neuroplasticity might be applied to neurorehabilitation strategies in neurologically impaired patients

Item Type: Article
Uncontrolled Keywords: Brain, neuroplasticity, recovery of function, rehabilitation, stimulation
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia)
Depositing User: Danilo Dezzi
Date Deposited: 15 Feb 2012 07:55
Last Modified: 15 Feb 2012 07:55
URI: http://eprints.bice.rm.cnr.it/id/eprint/3729

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