A real-time exposure system for electrophysiological recording in brain slices

Paffi, Alessandra and Pellegrino, Monica and Beccherelli, Romeo and Apollonio, Francesca and Liberti, Micaela and Platano , Daniela and Aicardi , Giorgio and D'inzeo, Guglielmo (2007) A real-time exposure system for electrophysiological recording in brain slices. IEEE Transactions on Microwave Theory and Techniques, 55 (11). pp. 2463-2471. ISSN 0018-9480

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Abstract—In order to study possible effects of microwave electromagnetic (EM) fields on neuronal activity, a real-time exposure system was designed and fabricated. The structure is suitable for electrophysiological recording in brain slices, a widely used in vitro methodology for investigations on neuronal function. The EM features of the structure were characterized both numerically and experimentally. Results indicate that the system is slightly radiating and that its field configuration produces minimum coupling with laboratory equipment. To determine the device efficiency, numerical and experimental dosimetry was conducted. The system exhibits high efficiency, with uniform distribution of the - and - fields and the specific absorption rate (SAR) in the biological sample.

Item Type: Article
Subjects: 500 Scienze naturali e Matematica > 500.2 Scienze fisiche
Depositing User: Danilo Dezzi
Date Deposited: 03 Jan 2013 12:57
Last Modified: 20 Mar 2013 15:47
URI: http://eprints.bice.rm.cnr.it/id/eprint/4466

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