Vitamin D inadequacy: the Italian picture

Rossini, Maurizio (2006) Vitamin D inadequacy: the Italian picture. Clinical cases in mineral and bone metabolism, 3 (1). pp. 43-49. ISSN 1971-3266

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Numerous epidemiological studies have assessed the prevalence of low serum 25-hydroxyvitamin D concentrations and have indicated that vitamin D inadequacy is a common problem in Italy, particularly in elderly women, and not only in inpatients with chronic disease or institutionalised subjects. There are important seasonal fluctuations in subjects living at home. Lower educational level, living in central Italy, smoking, and low intake of dairy products are associated with increased risk of vitamin D inadequacy. European and International studies have confirmed the high incidence of hypovitaminosis D in Italy, that appears unexpectedly more common than in northern European countries. Also, in Italy there is evidence that concentrations of 25-hydroxyvitamin D below 30 nmol/L is associated with secondary hyperparathyroidism, increased bone turnover, decreased bone mineral density at the hip, higher hip fracture prevalence, reduced muscular function and disability. The frequent finding of a high prevalence of vitamin D deficiency, in spite of the large amount of scientific data regarding the important role in the pathogenesis of skeletal and nonskeletal diseases, indicates that the treatments used up to now are insufficient or inadequate. A population-based strategy to correct this condition and new treatment methods with vitamin D that guarantee a better and long term compliance appear urgent. Preliminary experiences are heartening.

Item Type: Article
Uncontrolled Keywords: Vitamin D, hip fracture, osteoporosis, PTH
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 612 Fisiologia umana > 612.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 24 Jan 2014 12:10
Last Modified: 24 Jan 2014 12:10

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