Obstetric management in Rh alloimmunizated pregnancy

Cacciatore, Alessandra and Rapiti, Stefania and Carrara, Sabina and Cavalieri, Alessandro and Ermito, Santina and Dinatale, Angela and Imbruglia, Laura and Recupero, Stefania and La Galia, Tindara and Pappalardo, Elisa Maria and Accardi, Manuela Chiara (2009) Obstetric management in Rh alloimmunizated pregnancy. Journal of prenatal medicine, 3 (2). pp. 25-27. ISSN 1971-3290

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Rh alloimmunization occurs when maternal immune system is sensitized to D(Rh) erythrocyte surface antigens. The most common causes of maternal Rh alloimmunisation are blood transfusion and antepartum or intrapartum fetomaternal hemorrhage (abdominal trauma, abortion, ectopic pregnancy, invasive obstetric procedures, placental abruption, external cephalic version). The risk of alloimmunization is affected by several factors, including the degree of fetomaternal hemorrhage and maternal immune respons. Although the introduction of anti D prophylaxis reduced dramatically the rate of alloimmunization in susceptible women, his prevention is not universal and about 0.3% of susceptible women still become Rh D alloimmunized. The aim of this article is to review the management of the Rh alloimmunizated pregnant.

Item Type: Article
Uncontrolled Keywords: Alloimmunisation, fetal anemia, anti D prophilaxis
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.2 Ostetricia
Depositing User: Gianni Aiello
Date Deposited: 29 Apr 2013 09:42
Last Modified: 16 May 2013 12:09
URI: http://eprints.bice.rm.cnr.it/id/eprint/4723

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