Definition of bone necrosis by the pathologist

Fondi, Cristina and Franchi, Alessandro (2007) Definition of bone necrosis by the pathologist. Clinical cases in mineral and bone metabolism, 4 (1). pp. 21-26. ISSN 1971-3266

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Osteonecrosis is a common disorder that may go clinically unrecognized or may result in the collapse of the architecture of bone, determining severe anatomic alterations of the involved site. Osteonecrosis is not a specific disease entity, but rather the result of a number of conditions ultimately leading to an impairment of blood supply to the bone tissue, although there is evidence that modifications of bone remodelling activity and weakening of bone structure with formation of microfractures are implicated as well. According to the site involved and to the factors promoting its development, the morbid anatomy and histopathology of osteonecrosis show a different appearance. This review discusses the main skeletal manifestations of osteonecrosis, including subarticular avascular necrosis of the femoral head and of the knee, as well as osteonecrosis of the jaw.

Item Type: Article
Uncontrolled Keywords: Bone, necrosis, histopathology
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 612 Fisiologia umana > 612.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 20 Jan 2014 10:37
Last Modified: 20 Jan 2014 10:37

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