Treatment of bisphosphonates-associated osteonecrosis

Migliorati, Cesar A. and Hupp, Wendy S. and Migliorati, Erica K.J. (2007) Treatment of bisphosphonates-associated osteonecrosis. Clinical cases in mineral and bone metabolism, 4 (1). pp. 62-68. ISSN 1971-3266

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Abstract

This mini-review will focus on the management of a patient with bisphosphonate-associated osteonecrosis (BON). In order to review the subject the authors report a case of a patient with prostate cancer and metastatic bone disease who was treated with zoledronic acid. Prior to cancer the patient was treated with risedronate for osteopenia but had discontinued this treatment when cancer was diagnosed. During the description of each aspect of the case, a discussion of the rationale used for the case management is presented with supportof the available literature. Aspects of interest include the diagnosis of BON, the risk factor for BON for this particular patient, the decision making process for the management of acute and long-term oral cavity problems, and the introduction of high intensity laser therapy to help control pain and reduce infection and local bacterial load.

Item Type:	Article
Uncontrolled Keywords:	Bisphosphonates, osteonecrosis, complication, treatment, laser therapy
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 612 Fisiologia umana > 612.7 Sistema muscoloscheletrico, tegumento
Depositing User:	Danilo Dezzi
Date Deposited:	20 Jan 2014 10:12
Last Modified:	20 Jan 2014 10:12
URI:	http://eprints.bice.rm.cnr.it/id/eprint/4844

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