The link between osteoporosis and cardiovascular disease

Farhat, Ghada N. and Cauley, Jane A. (2008) The link between osteoporosis and cardiovascular disease. Clinical cases in mineral and bone metabolism, 5 (1). pp. 19-34. ISSN 1971-3266

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Cardiovascular disease (CVD) and osteoporosis are common age-related conditions associated with significant morbidity, mortality, and disability. Traditionally, these two conditions were considered unrelated and their coexistence was attributed to independent age-related processes. However, an increasing body of biological and epidemiological evidence has provided support for a link between the two conditions that cannot be explained by age alone. Several hypotheses have been proposed to explain the link between osteoporosis and CVD including: 1) shared risk factors, 2) common pathophysiological mechanisms, 3) common genetic factors, or 4) a causal association. This review highlights the epidemiologic literature on the association of bone density with cardiovascular mortality, cardiovascular morbidity, and subclinical measures of atherosclerosis. It also summarizes the different potential mechanisms involved in the link between osteoporosis and CVD.

Item Type: Article
Uncontrolled Keywords: Osteoporosis, bone mineral density, cardiovascular disease, atherosclerosis, vascular calcification
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 612 Fisiologia umana > 612.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 17 Jan 2014 12:54
Last Modified: 17 Jan 2014 13:04

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