Gorucu, Yasin and Albayram, Sait and Balci, Belgin and Hasiloglu, Zehra Isik and Yenigul, Kubilay and Yargic, Fatma and Keserb, Zafer and Kantarci, Fatih and Kiris, Adem (2011) Cerebrospinal fluid flow dynamics in patients with multiple sclerosis: a phase contrast magnetic resonance study. Functional Neurology : New Trends in Interventional Neurosciences, XXVI (4). pp. 215-220. ISSN 0393-5264
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Abstract
Cerebrospinal fluid (CSF) flow dynamics, which supposedly have a strong relationship with chronic cerebrospinal venous insufficiency (CCSVI), might be expected to be affected in multiple sclerosis (MS) patients. In this study, CSF flow at the level of the cerebral aqueduct was evaluated quantitatively by phase contrast magnetic resonance imaging (PC-MRI) to determine whether CSF flow dynamics are affected in MS patients. We studied 40 MS patients and 40 healthy controls using PC-MRI. We found significantly higher caudocranial(p=0.010) and craniocaudal CSF flow volumes(p=0.015) and stroke volume (p=0.010) in the MS patients compared with the controls. These findings may support the venous occlusion theory, but may also be explained by atrophy-dependent ventricular dilatation independent of the venous theory in MS patients.
| Item Type: | Article |
|---|---|
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) |
| Depositing User: | Chiara Bisogno |
| Date Deposited: | 10 Sep 2019 12:47 |
| Last Modified: | 10 Sep 2019 14:43 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/5101 |
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