Current strategy for detection and diagnosis of hyperglycemic disorders in pregnancy

Santamaria, Angelo and Cignini, Pietro and Trapanese, Angela and Bonalumi, Silvia (2011) Current strategy for detection and diagnosis of hyperglycemic disorders in pregnancy. Journal of prenatal medicine, 5 (1). pp. 15-17. ISSN 1971-3290

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Abstract

Gestational diabetes mellitus (GDM) is a metabolic alteration frequently found in pregnant women. In women with GDM, failure of pancreatic beta-cells to adapt the production of insulin at the increased metabolic demand in pregnancy, results in a inadequate insulin response, with consequent hyperglycemia. The criteria currently used for the diagnosis of GDM are too restrictive as some author suggested that different degrees of hyperglycemia, even though not diagnostic for diabetes, increase the risks of adverse perinatal outcomes (large for gestational age (LGA), higher rate of cesarean section, neonatal hypoglycemia, respiratory distress, perinatal mortality). The objective of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study was to clarify the associations of levels of maternal glucose, lower than those diagnostic of diabetes, with perinatal outcome, defining a new overall strategy recommended for detection and diagnosis of hyperglycemic disorders in pregnancy.

Item Type:	Article
Uncontrolled Keywords:	Gestational diabetes mellitus (GDM), HAPO study, hyperglycemic disorders, pregnancy
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.3 Malattie e complicazioni della gravidanza
Depositing User:	Gianni Aiello
Date Deposited:	20 May 2013 16:21
Last Modified:	20 May 2013 16:21
URI:	http://eprints.bice.rm.cnr.it/id/eprint/5142

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