The use of uterine artery doppler as a predictive tool for adverse gestational outcomes in pregnant patients with autoimmune and thrombophilic disease

Capucci, Roberta and Pivato, Elena and Carboni, Simona and Mossuto, Elena and Castellino, Gabriella and Padovan, Melissa and Govoni, Marcello and Marci, Roberto and Patella, Alfredo (2011) The use of uterine artery doppler as a predictive tool for adverse gestational outcomes in pregnant patients with autoimmune and thrombophilic disease. Journal of prenatal medicine, 5 (2). pp. 54-58. ISSN 1971-3290

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Abstract

Objectives: To verify whether Doppler velocimetry on the uterine arteries can be used to single out abnormal hemodynamic adjustments in the uteroplacental district and to prognose adverse gestational outcomes in pregnant women with autoimmune and trombophilic disease. Methods: The study included 67 patients divided into 3 groups selected by a developed pathology. Attention was given to the performance of the Resistance Index (RI) in Doppler velocimetry checks at 10th, 16th- 18th, 21st and 28th weeks of gestation. Results: A significant correlation between Doppler values at week 21st and development of preeclampsia was observed (p <0.05) in the three patient groups. High Doppler values at the 21st week were found to be strongly associated (p <0.01) with preterm delivery. We also observed a significant correlation (p <0.05) between high Doppler values at week 21st and low weight at birth. Doppler was found to have a predictive power for gestational adverse outcomes already at week 16th. Conclusion: RI values of more than 0.58 (taken as a cut-off) at 16/18th weeks allowed us to identify the category most at risk, if confirmed at 21 weeks.

Item Type:	Article
Uncontrolled Keywords:	Pregnancy, autoimmune diseases, doppler, complications
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.2 Ostetricia
Depositing User:	Gianni Aiello
Date Deposited:	20 May 2013 16:48
Last Modified:	20 May 2013 16:48
URI:	http://eprints.bice.rm.cnr.it/id/eprint/5186

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