De Salvo, Simona and Bramanti, Placido and Marino, Silvia (2012) Clinical differentiation and outcome evaluation invegetative and minimally conscious state patients:the neurophysiological approach. Functional Neurology : New Trends in Interventional Neurosciences, XXVII (3). pp. 147-154. ISSN 0393-5264
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Abstract
Long-term oral therapy with levodopa is associatedwith the development of motor fluctuations and dyski-nesia in a large percentage of patients with Parkinson’sdisease (PD). Motor complications are associated witha number of non-motor symptoms and have a negativeimpact on disability and quality of life. There are threetherapeutic options available for the management ofpatients at this advanced stage: high frequency deepbrain stimulation, continuous subcutaneous infusionof apomorphine, and continuous intestinal infusion oflevodopa/carbidopa. On the basis of published dataand in consideration of the risk-benefit profile of cur-rent therapeutic strategies, we here propose an algo-rithm to help clinicians select the most suitable treat-ment option for patients with advanced PD.
| Item Type: | Article |
|---|---|
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) |
| Depositing User: | Chiara Bisogno |
| Date Deposited: | 10 Sep 2019 12:56 |
| Last Modified: | 10 Sep 2019 14:44 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/5254 |
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