Doppler velocimetry of ductus venous in preterm fetuses with brain sparing effect: neonatal outcome

Cosmo, Ynesmara Coelho and Araujo, Júnior, Edward and Moreira de Sà, Renato Augusto and de Carvalho, Paulo Roberto Nassar and Rosiane, Mattar and Lopez, Laudelino Marques and Nardozza, Luciano Marcondes Machado and De Souza, Eduardo and Moron, Antonio Fernandez (2012) Doppler velocimetry of ductus venous in preterm fetuses with brain sparing effect: neonatal outcome. Journal of prenatal medicine, 6 (3). pp. 40-46. ISSN 1971-3290

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Abstract

Objective: to evaluate the relationship between ductus venous (DV) and Doppler velocimetry in neonatal outcome in severe compromised preterm fetuses. Methods: the study was designed as an observational and cross-sectional study with 52 premature neonates with brain sparing effect. The criteria of neonatal severe morbidity were: severe intraventricular hemorrhage (grades 3 or 4), retinopathy of prematurity (grade 3 or 4), cystic periventricular leukomalatia, bronchopneumo dysplasia and neonatal mortality. The fetuses were divided in two groups: group 0 - all the fetuses with ventricular systole/atrial contraction (S/A) in DV ratio values less them 3.4; group 1 - fetuses with values of S/A ratio greater than 3.4. Results: 42% of fetuses showed abnormal S/A ratio in DV and 48% showed birth weight below percentile 3 for gestational age. There was no statistical significance comparing the 02 groups according to bronchopneumo dysplasia, retinopathy of prematurity (grade 3 or 4) and intraventricular hemorrhage (grade 3 or 4). Only one fetus presented cystic periventricular leukomalatia. We found statistically significant association between abnormal DV S/A ratio and neonatal mortality (CI 95%, 1.28 -38.22, p< 0.002). Conclusions: our results suggest that abnormal DV blood flow detected by Doppler examination isnʼt associated with severe neonatal morbidity but with neonatal mortality.

Item Type:	Article
Uncontrolled Keywords:	Fetus, Doppler, ductus venosus, brain sparing effect, morbidity, mortality
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.2 Ostetricia
Depositing User:	Gianni Aiello
Date Deposited:	29 May 2013 11:57
Last Modified:	10 Apr 2014 08:42
URI:	http://eprints.bice.rm.cnr.it/id/eprint/5393

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