Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence

Cignini, Pietro and Giorlandino, Claudio and Padula, Francesco and Dugo, Nella and Cafà, Ester Valentina and Spata, Anna (2012) Epidemiology and risk factors of amniotic band syndrome, or ADAM sequence. Journal of prenatal medicine, 6 (4). pp. 59-63. ISSN 1971-3290


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Amniotic band sequence (ABS) is the term applied to a wide range of congenital anomalies, most typically limb and digital amputations and constriction rings, that occur in association with fibrous bands (1). These alterations may be associated or not with cutaneous and visceral abnormalities. This work, which is a literature review, examines several studies that relate to cases of amniotic band syndrome (SBA). In particular, our attention was focused on the causes and pathogenesis of the SBA. These for the most part are still unknown, but from what we observe in different jobs, are due to a mechanism of vascular damage. Therefore in this paper we examine chemical risk factors, like smoking, drug use, maternal hyperglycemia, mechanical risk factors such as the puncture of the amniotic sac after amniocentesis. We also speak of the altitude as a risk factor related to blood pressure, of the increased incidence of disease in primigravid, in women with a low level of education, in which the pregnancy was not planned, and then we talk of a higher incidence in young fathers and of the role of familiarity.

Item Type: Article
Uncontrolled Keywords: Digital amputation, constriction rings, vascular damage, chemical risk factors, mechanical risk factors, familiarity
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.3 Malattie e complicazioni della gravidanza
Depositing User: Gianni Aiello
Date Deposited: 29 May 2013 12:22
Last Modified: 29 May 2013 12:22
URI: http://eprints.bice.rm.cnr.it/id/eprint/5433

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