Periprosthetic bone density as outcome of therapeutic response

Iolascon, Giovanni and Di Pietro, Gioconda and Capaldo, Annarita and Gioia, Carmine and Gatto, Salvatore and Gimigliano, Francesca (2010) Periprosthetic bone density as outcome of therapeutic response. Clinical cases in mineral and bone metabolism, 7 (1). pp. 27-31. ISSN 1971-3266

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The bone surrounding a prosthetic implant normally experiences a progressive quantitative reduction as a result of stress shielding and wear debris production, that can lead to the aseptic loosening of the implant. Dual-energy X-ray absorptiometry (DXA), using software algorithms, can ensure a surrogate measure of load redistribution after the implant of the prosthetic components and can be a valid tool to evaluate the efficacy of pharmacological therapy to reduce the periprosthetic bone loss. In several animal and human studies DXA has been able to quantify antiresorptive action of bisphosphonates in the periprosthetic area

Item Type: Article
Uncontrolled Keywords: DXA, periprosthetic bone loss, pharmacological treatment
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 14 Jan 2014 10:29
Last Modified: 14 Jan 2014 10:29

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