Metachronous Paget’s disease of the breast: case report

Gubitosi, Adelmo and Moccia, G and Malinconico, Francesca Antonella and Iside, Giovanni and Gilio, Ffrancesco and Cognetti, C. and Foroni, Fabrizio and Docimo, Giovanni and Ruggiero, Roberto and Docimo, Ludovico and Agresti, Massimo (2009) Metachronous Paget’s disease of the breast: case report. Il giornale di chirurgia, 30 (4). pp. 153-155. ISSN 1971-145X

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Paget breast disease is a kind of intraductal carcinoma that through an intracanalicular diffusion invades the basal epidermical layer,reaching the areola and nipple, producing a typical erythematous desquamative eczematous-like lesion. This neoplasia can remain undetected for a long time and inadequately treated as a dermatological affection. Synchronous or metachronous lesions are very uncommon. Surgical choice is conditioned by the presence of a tumor below the epidermical lesion, by its dimensions, and by the possible lymph node involvement. Surgical therapy can be radical or conservative. From our experience we think that lesion biopsy is always necessary to formulate a correct diagnosis and to schedule an appropriate therapeutic approach. In our case, a biopsy was performed first, then on the basis of the frozen section analysis a radical mastectomy with axillary third level lymph nodes dissection, because of the large dimensions of thelesion and the previous history of a methachronous lesion

Item Type: Article
Uncontrolled Keywords: Paget disease, Breast cancer, Surgery
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User: Nadia Del Gobbo
Date Deposited: 04 Feb 2016 16:38
Last Modified: 04 Feb 2016 16:38

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