Chemioipertermia intraperitoneale laparoscopica nel trattamento dell’ascite maligna. Case report

Graziosi, Luigina and Bugiantella, Walter and Cavazzoni, Emanuel and Donini, Annibale (2009) Chemioipertermia intraperitoneale laparoscopica nel trattamento dell’ascite maligna. Case report. Il giornale di chirurgia, 30 (5). pp. 237-239. ISSN 1971-145X

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Malignant ascites is a pathological condition, due to several abdominal and extra-abdominal neoplasms, representing a difficult challenge in treatment. Different medical and surgical options have been proposed, but none of them have shown efficacy, leading only to partial and temporary relief of symptoms. Laparoscopic intraperitoneal chemotherapy may be a valid therapeutic option in patients in whom medical therapies have failed and peritoneovenous shunting is contraindicatd. A 49-years old woman with malignant ascites, secondary to peritoneal localization of right pleural mesothelioma, underwent, after failure of medical therapy, laparoscopic intraperitoneal chemotherapy (with Cisplatin 25 mg/m2/L and Doxorubicin 7 mg/m2/L). An important and lasting reduction of ascites and abdominal symptoms was documented till the exitus, due to pulmonary embolism after 11 months.Laparoscopic intraperitoneal chemotherapy may be a good therapeutic option to palliative malignant ascites in patient not eligible for a radical cytoreductive treatment, but further investigations are needed to standardized dosage and perfusion procedure

Item Type: Article
Uncontrolled Keywords: Malignant ascites, Hypertermic chemotherapy, Laparoscopy, Surgery
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User: Nadia Del Gobbo
Date Deposited: 08 Feb 2016 14:20
Last Modified: 08 Feb 2016 14:20

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