Pharmaco-economic issues in the treatment of severe osteoporosis

Piscitelli, Prisco and Chitano, Giovanna and Greco, Marco and Benvenuto, Marco and Sbenaglia, Enzo and Coli, Giuseppe and Migliore, Alberto and Granata, Mauro and Iolascon, Giovanni and Gimigliano, Raffaele and Baggiani, Angelo and Distante, Alessandro and Tarantino, Umberto and Rizzuti, Carla and Brandi, Maria Luisa (2010) Pharmaco-economic issues in the treatment of severe osteoporosis. Clinical cases in mineral and bone metabolism, 7 (1). pp. 61-64. ISSN 1971-3266

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Introduction: clinical guidelines recommend to identify and treat people at high risk of fracture. Methods: we have carried out a simulation concerning pharmaco-economic issues in the treatment of severe osteoporosis and particularly those people with previous femoral fragility fractures, assuming that only 13.1% of hip fractured patients had started a proper antifracture therapy, as shown by the analysis of the Tuscany regional database. Results: Annual costs sustained by the Italian healthcare system for treating hip fractured patients all over Italy have been estimated to range from 2 560 000 in year 2000 to 3 291 750 in year 2005, representing only 0,3% of the overall costs sustained because of hip fractures in Italy. Conclusions: Sixty percent of the pharmacological costs can be considered as ineffective from a therapeutic point of view because patients were assuming their drugs only for 6 months. There is a need for specific codification of osteoporotic fragility fractures at hospital admissions and for implementing regional strategies aimed to reduce hip re-fractures by increasing the number of patients on treatment and incrementing adherence to treatment

Item Type: Article
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 13 Jan 2014 14:02
Last Modified: 28 Sep 2015 08:13

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