New biomaterials for bone regeneration

Matassi, Fabrizio and Nistri, Lorenzo and Paez, Diana Chicon and Innocenti, Massimo (2011) New biomaterials for bone regeneration. Clinical cases in mineral and bone metabolism, 8 (1). pp. 21-24. ISSN 1971-3266

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Bone-grafting techniques either with autografts or allografts still represent a challenge for reconstructive surgery. Allografts and autografts are the current strategies for filling bone defects and subsequent repair but each have drawbacks. Synthetic bone-graft substitutes, developed in an effort to overcome the inherent limitations of autograft and allograft, represent an alternative strategy. Synthetic bone graft substitutes have the goal of mimicking the physical and mechanical nature of native tissue and to promote osteoconduction for bone regeneration. In addition these substitutes are capable to release drugs or growth factors in a temporally and spatially manner. Some biomaterials are employed to design biomimetic scaffold such as natural and synthetic polymers, ceramics, metallics and composites. The purpose of this paper is to provide an overview of the main biomaterials used for bone reconstruction

Item Type: Article
Uncontrolled Keywords: Tissue engineering, scaffold, biomaterials, regenerative medicine
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 10 Jan 2014 12:01
Last Modified: 10 Jan 2014 12:01

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