Osteosynthetic improvement of osteoporotic bone: prevention surgery

Giannini, Sandro and Luciani, Deianira and Chiarello, Eugenio and Cadossi , Matteo and Tedesco, Giuseppe and Hoque, Martha and Gnudi, Saverio (2011) Osteosynthetic improvement of osteoporotic bone: prevention surgery. Clinical cases in mineral and bone metabolism, 8 (1). pp. 51-54. ISSN 1971-3266

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A prior osteoporotic femoral neck fracture (FNF) doubles the risk of a second, contralateral hip fracture. Pharmacological prevention of osteoporotic fractures is cost-effective but medication compliance and persistence rates are suboptimal. The aim of our study was to evaluate the safety and effectiveness of a device developed for the surgical prevention of an additional contralateral FNF in elderly osteoporotic patients. Only patients with a T score ≤ -2.5 were enrolled and randomized either to receive (Group A) or not receive (Group B) surgical prevention. Sixty-seven patients were enrolled. The mean follow-up was 16 months (range 1 to 22). To date, no contralateral FNF has been reported in either group. In Group A, no device-related complications were recorded. Twelve patients reported one or more falls and in four cases a non-femoral fragility fracture occurred. The main problem with pharmacological prevention is therapy adherence and the extensive period needed for only a slight improvement in bone strength. Surgical prevention is a potential solution for avoiding the occurrence of a second contralateral FNF. Nevertheless, a longer follow-up and a larger cohort of patients is necessary in order to verify the true effectiveness of the surgical prevention in elderly osteoporotic patients

Item Type: Article
Uncontrolled Keywords: Femoral neck fractures; osteoporosis; surgical prevention
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 10 Jan 2014 11:41
Last Modified: 10 Jan 2014 11:41
URI: http://eprints.bice.rm.cnr.it/id/eprint/5964

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