Surgery in hepatic and extrahepatic colorectal metastases

Favero, Alessandro and Benzoni, Enrico and Zompicchiatti, Aron and Rossit, Luca and Bresadola, Fabrizio and De Anna, Dino and Uzzau, Alessandro (2007) Surgery in hepatic and extrahepatic colorectal metastases. Il giornale di chirurgia, 28 (8-9). pp. 307-311. ISSN 1971-145X

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Extrahepatic disease (EHD) has been considered a contraindication to hepatectomy. Over the last few years, some series reported interesting 5-year survival rates after resection with hepatic colorectal metastases and EHD free margins. Between August 1989 and October 2005, 116 patients underwent liver resection for colorectal metastases at Surgical Department of the University of Udine, Italy. Among these, we reviewed the data of 5 patients affected by EHD. In 3 patients there were also an anastomotic recurrence of the primarytumor, in 3 patients diaphragm was infiltrated by contiguous liver metastases. We performed in all the patients minor liver resections. We have associated the radiofrequence ablation of a lesion not surgically resectable with liver resection in one case. The surgical procedure was always considered as curative. We observed no case of operative mortality. The mean survival of the entire cohort is 23.2 months (range 4- 42 months). Our study, even if based upon a limited number of patients, supports the thesis that extrahepatic disease in patients affected by colorectal cancer with hepatic metastases should not be considered as an absolute contraindication to liver resection especially for the cases in with local radical cure exeresis is achievable.

Item Type: Article
Uncontrolled Keywords: Colorectal cancer, Liver metastases, Liver resection; Cancro colorettale, Metastasi epatiche, Resezione epatica
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User: Chiara D'Arpa
Date Deposited: 04 Oct 2013 15:49
Last Modified: 04 Oct 2013 15:49

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