Pyoderma gangrenosum of the “sinus mammarum” in ulcerative colitis

Angiò, Luigi Giuseppe and Pirrone, Giovanni and Rivoli, Giovanna and Fracassi, Maria Grazia and Rosato, Alessio and Piazzese, Enrico M. S. and Pacilè, Vincenzo and Sfuncia, Giuseppe and Fiumara, Frank (2003) Pyoderma gangrenosum of the “sinus mammarum” in ulcerative colitis. Il giornale di chirurgia, 24 (6/7). pp. 247-254. ISSN 1971-145x

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The first part of this article deals with the report of a patient suffe - ring from pyoderma gangrenosum of the “sinus mammarum” associa - ted with asymptomatic ulcerative colitis. This is followed by a revision of the present epidemiological, etiological, pathogenetic and clinical knowledges about this systemic manifestation of chronic phlogosis of the colon. The Authors have analysed the treatment for this condition and emphasized the resistance of the cutaneous ulcer encountered to conven - tional medical therapy of the underlying colonic disease which proved to be efficacious only on the latter; this led to integrate traditional treatment with the use of perilesional injections of small doses of calcic heparin as an alternative to immunosuppressive drugs or surgery. Topical antithrombotic treatment, which can be justified by the histo - logical findings of phenomena of the vasculitis in the edge of pyoderma gangrenosum, demonstrated to be crucial and represents a peculiarity in the case here reported, which is unique in the literature as far as the Authors know, since it has not been experimented by anyone else.

Item Type: Article
Uncontrolled Keywords: Colite ulcerosa, Complicazioni extraintestinali, Pioderma gangrenoso
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User: Chiara D'Arpa
Date Deposited: 23 Oct 2013 15:21
Last Modified: 23 Oct 2013 15:21

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