Multiple primary malignancies. A rare case of five metachronous tumours

Mosca, Franco and Stracqualursi, Antonio and Persi, Achille and Portale, Teresa Rosanna and Zappalà, Orazio and Latteri, Saverio F. (2005) Multiple primary malignancies. A rare case of five metachronous tumours. Il giornale di chirurgia, 26 (8/9). pp. 302-306. ISSN 1971-145x

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The Authors report on a patient admitted several times for the occurrence of five multiple metachronous primary malignancies (laryngeal carcinoma, endometrial adenocarcinoma, rectal cancerous polyp, Vater papilla carcinoma and transverse colon cancer). All five carcinomas were independent primary cancers and the lenghty time intervals between the onsets of each individual tumours confirm their independent non-metastatic origin. Classification, pathogenesis, genetic and environmental interactions of these tumours are discussed; in the case reported a family history of colon cancer was present, while no genetic markers abnormalities or chronic exposure to carcinogens were found. The case report suggests that an aggressive, appropriate surgical approach together with a through follow-up monitoring offers a chance of long-term survival for patients with metachronous malignant primary tumours.

Item Type: Article
Uncontrolled Keywords: Multiple primary malignancies, Metachronous tumours; Neoplasie maligne primitive multiple, Tumori metacroni
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User: Chiara D'Arpa
Date Deposited: 18 Nov 2013 13:28
Last Modified: 18 Nov 2013 13:28

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