Mortality and prognosis in patients with neurogenic orthostatic hypotension

Maule, Simona and Milazzo, Valeria and Maule, Milena Maria and Di Stefano, Cristina and Milan, Alberto and Veglio, Franco (2012) Mortality and prognosis in patients with neurogenic orthostatic hypotension. Functional Neurology; New Trends in Interventional Neurosciences, XXVII (2). pp. 101-106. ISSN 1971-3274

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Abstract

The prognosis of neurogenic orthostatic hypotension (NOH) has been poorly studied. The aim of this study was to evaluate retrospectively comorbidities and causes of death in patients with NOH. Clinical information and causes of death were obtained for 104 patients (45 with multiple system atrophy, 9 with pure autonomic failure, 43 with Parkinson’s disease, and 7 with other types of autonomic neuropathy) referred to the Autonomic Unit from 1996 to 2009. Cardiovascular diseases (hypertension, cardiac comorbidities, atrial fibrillation and heart failure) were present in 53 (51%) NOH patients. At the end of follow-up, 44 patients were deceased. Type of NOH was the main factor associated with mortality. The main causes of death were infectious/respiratory (54%) and cardiac (16%). In NOH patients, cardiovascular diseases are frequent, although mortality is mainly due to infectious and respiratory causes. Detection of cardiovascular diseases may be useful in the choice of anti-hypotensive treatments.

Item Type:	Article
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia)
Depositing User:	Chiara Bisogno
Date Deposited:	10 Sep 2019 14:52
Last Modified:	10 Sep 2019 14:52
URI:	http://eprints.bice.rm.cnr.it/id/eprint/7731

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