Biodegradable synthetic scaffolds for tendon regeneration

Reverchon, Ernesto and Baldino, Lucia and Cardea, Stefano and De Marco, Iolanda (2012) Biodegradable synthetic scaffolds for tendon regeneration. M.L.T.J. Muscles, Ligaments and Tendons Journal, 2 (3). pp. 181-186. ISSN 2240-4554

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Abstract

Tissue regeneration is aimed at producing biological or synthetic scaffolds to be implanted in the body for regenerate functional tissues. Several techniques and materials have been used to obtain biodegradable synthetic scaffolds, on which adhesion, growth, migration and differentiation of human cells has been attempted. Scaffolds for tendon regeneration have been less frequently proposed, because they have a complex hierarchical structure and it is very difficult to mimic their peculiar mechanical properties. In this review, we critically analyzed the proposed materials and fabrication techniques for tendon tissue engineering and we indicated new preparation processes, based on the use of supercritical fluids, to produce scaffolds with characteristics very similar to the native tendon structure

Item Type:	Article
Uncontrolled Keywords:	Cells cultivation, supercritical fluids, synthetic scaffolds, tendon tissue engineering
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	16 Apr 2014 16:17
Last Modified:	16 Apr 2014 16:17
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8140

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