Tissue engineering for skeletal muscle regeneration

Rizzi, Roberto and Bearzi, Claudia and Mauretti, Arianna and Bernardini, Sergio and Cannata, Stefano and Gargioli, Cesare (2012) Tissue engineering for skeletal muscle regeneration. M.L.T.J. Muscles, Ligaments and Tendons Journal, 2 (3). pp. 230-234. ISSN 2240-4554

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Stem cells and regenerative medicine have obtained a remarkable consent from the scientific community for their promising ability to recover aged, injured and diseased tissue. However, despite the noteworthy potential, hurdles currently hinder their use and clinical application: cell survival, immune response, tissue engraftment and efficient differentiation. Hence a new interdisciplinary scientific approach, such as tissue engineering, is going deep attempts to mimic neo-tissue-genesis as well as stem cell engraftment amelioration. Skeletal muscle tissue engineering represents a great potentiality in medicine for muscle regeneration exploiting new generation injectable hydrogel as scaffold supporting progenitor/stem cells for muscle differentiation reconstructing the natural skeletal muscle tissue architecture influenced by matrix mechanical and physical property and by a dynamic environment

Item Type: Article
Uncontrolled Keywords: Skeletal muscle, tissue engineering, hydrogel
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User: Danilo Dezzi
Date Deposited: 16 Apr 2014 16:36
Last Modified: 16 Apr 2014 16:36
URI: http://eprints.bice.rm.cnr.it/id/eprint/8147

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